BLAST table : Urd_00060

	accession	DB	alignment	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q9RP99_STRFR (Q9RP99)			0.0	763	100%	UniProt GenBank	Glycosyl transferase	urdGT1c	Streptomyces fradiae Streptomyces roseoflavus
2	Q9RPA1_STRFR (Q9RPA1)			0.0	673	92%	UniProt GenBank	Glycosyl transferase	urdGT1b	Streptomyces fradiae Streptomyces roseoflavus
3	Q2HR28_9ACTO (Q2HR28)			1e-122	442	59%	UniProt GenBank	Putative O-glycosyltransferase	schS9	Streptomyces sp. SCC 2136
4	D7BZS3_STRBB (D7BZS3)			1e-119	434	60%	UniProt GenBank	Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B	SBI_06858	Streptomyces bingchenggensis (strain BCW-1)
5	C4NYL1_9ACTO (C4NYL1)			1e-113	414	59%	UniProt GenBank	SaqGT4	saqGT4	Micromonospora sp. Tu 6368
6	A4GV88_9ACTO (A4GV88)			1e-109	400	55%	UniProt GenBank	Glycosyltransferase	holL	Streptomyces sp. Tu1156
7	C4NYL0_9ACTO (C4NYL0)			1e-107	392	56%	UniProt GenBank	SaqGT3	saqGT3	Micromonospora sp. Tu 6368
8	Q9ZGB8_STRCY (Q9ZGB8)			1e-107	392	55%	UniProt GenBank	Glycosyl transferase homolog	lanGT1	Streptomyces cyanogenus
9	D7BZS5_STRBB (D7BZS5)			2e-99	367	53%	UniProt GenBank	IroB	SBI_06860	Streptomyces bingchenggensis (strain BCW-1)
10	A4GV86_9ACTO (A4GV86)			2e-96	357	52%	UniProt GenBank	Glycosyltransferase	holA	Streptomyces sp. FU107
11	Q6QR18_STRGL (Q6QR18)			5e-96	356	54%	UniProt GenBank	Glycosyl transferase		Streptomyces globisporus
12	Q9ZGB4_STRCY (Q9ZGB4)			2e-91	341	52%	UniProt GenBank	Glycosyl transferase homolog	lanGT3	Streptomyces cyanogenus
13	E5RLN7_9ACTO (E5RLN7)			1e-77	294	44%	UniProt GenBank	Putative glycosyltransferase	pnxGT2	Streptomyces sp. TA-0256
14	Q4JHR2_9PSEU (Q4JHR2)			3e-57	227	37%	UniProt GenBank	BusG	busG	Saccharopolyspora pogona
15	Q9ALM8_9PSEU (Q9ALM8)			9e-56	222	36%	UniProt GenBank	Probable NDP-rhamnosyltransferase	spnG	Saccharopolyspora spinosa
16	D7BZR2_STRBB (D7BZR2)			2e-54	217	38%	UniProt GenBank	Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B	SBI_06847	Streptomyces bingchenggensis (strain BCW-1)
17	C0JWA0_9ACTO (C0JWA0)			2e-51	208	38%	UniProt GenBank	PokGT2	pokGT2	Streptomyces diastatochromogenes
18	D8I4K0_AMYMU (D8I4K0)			3e-51	207	37%	UniProt GenBank	Putative glycosyl transferase	AMED_5414	Amycolatopsis mediterranei (strain U-32)
19	D9SZA9_MICAI (D9SZA9)			5e-51	206	41%	UniProt GenBank	Putative uncharacterized protein	Micau_3719	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
20	E8S036_MICSL (E8S036)			4e-50	203	41%	UniProt GenBank	Putative uncharacterized protein	ML5_4680	Micromonospora sp. (strain L5)
21	D8I4K4_AMYMU (D8I4K4)			1e-47	195	35%	UniProt GenBank	Putative glycosyl transferase	AMED_5418	Amycolatopsis mediterranei (strain U-32)
22	Q4R0L9_STRCX (Q4R0L9)			2e-47	194	36%	UniProt GenBank	ChaGT1 protein	chaGT1	Streptomyces chartreusis
23	Q70J80_STRGR (Q70J80)			5e-46	190	37%	UniProt GenBank	Glycosyltransferase	cmmGI	Streptomyces griseus subsp. griseus
24	Q194P9_STRAA (Q194P9)			3e-45	187	35%	UniProt GenBank	Glycosyltransferase	mtmGIII	Streptomyces argillaceus
25	Q70J70_STRGR (Q70J70)			3e-45	187	35%	UniProt GenBank	Glycosyltransferase	cmmGIII	Streptomyces griseus subsp. griseus
26	O87831_STRAT (O87831)			3e-45	187	34%	UniProt GenBank	Glycosyltransferase	oleG2	Streptomyces antibioticus
27	Q70J68_STRGR (Q70J68)			8e-44	182	34%	UniProt GenBank	Glycosyltransferase	cmmGIV	Streptomyces griseus subsp. griseus
28	Q70J67_STRGR (Q70J67)			9e-44	182	38%	UniProt GenBank	Glycosyltransferase	cmmGII	Streptomyces griseus subsp. griseus
29	Q0R4N0_STRAT (Q0R4N0)			1e-43	182	37%	UniProt GenBank	ChlC6		Streptomyces antibioticus
30	Q0R4P9_STRAT (Q0R4P9)			1e-43	182	35%	UniProt GenBank	ChlC7		Streptomyces antibioticus
31	D2AY79_STRRD (D2AY79)			3e-43	181	39%	UniProt GenBank	IroB	Sros_4185	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
32	Q76KZ6_STRHA (Q76KZ6)			3e-43	181	33%	UniProt GenBank	Glycosyltransferase	vinC	Streptomyces halstedii
33	A1C188_9ACTO (A1C188)			4e-43	180	36%	UniProt GenBank	L-rhamnosyltransferase		Streptomyces echinatus
34	Q8GHC2_9ACTO (Q8GHC2)			5e-43	180	36%	UniProt GenBank	Glycosyltransferase	cloM	Streptomyces roseochromogenes subsp. oscitans
35	B3TMP5_9ACTO (B3TMP5)			5e-43	179	35%	UniProt GenBank	Glycosyltransferase	KijC1	Actinomadura kijaniata
36	B3TMN6_9ACTO (B3TMN6)			3e-42	177	33%	UniProt GenBank	Glycosyltransferase	KijA4	Actinomadura kijaniata
37	B5L6L8_MICCH (B5L6L8)			3e-42	177	31%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
38	Q194Q0_STRAA (Q194Q0)			4e-42	177	35%	UniProt GenBank	Glycosyltransferase	mtmGIV	Streptomyces argillaceus
39	D4QF41_9ACTO (D4QF41)			6e-42	176	36%	UniProt GenBank	Rhamnosyltransferase	lipB1	Streptomyces sp. SANK 60405
40	Q9RN63_STRNO (Q9RN63)			1e-41	175	35%	UniProt GenBank	Putative glycosyl transferase	snogE	Streptomyces nogalater
41	D8I4I4_AMYMU (D8I4I4)			1e-41	175	35%	UniProt GenBank	Putative glycosyl transferase	AMED_5398	Amycolatopsis mediterranei (strain U-32)
42	Q2P9Y9_9ACTO (Q2P9Y9)			2e-41	174	34%	UniProt GenBank	Glycosyl transferase	stfG	Streptomyces steffisburgensis
43	E3IZG9_FRASU (E3IZG9)			2e-41	174	36%	UniProt GenBank	Putative uncharacterized protein	FraEuI1c_4748	Frankia sp. (strain EuI1c)
44	Q54824_STRPE (Q54824)			2e-41	174	35%	UniProt GenBank	Glycosyl transferase	dnrS	Streptomyces peucetius
45	D8I4J9_AMYMU (D8I4J9)			8e-41	172	37%	UniProt GenBank	Putative glycosyl transferase	AMED_5413	Amycolatopsis mediterranei (strain U-32)
46	Q83WE1_MICGR (Q83WE1)			1e-40	172	34%	UniProt GenBank	Glycosyltransferase	mycB	Micromonospora griseorubida
47	A4GV85_9ACTO (A4GV85)			1e-40	172	36%	UniProt GenBank	Glycosyltransferase	holC	Streptomyces rufochromogenes
48	A8WDM7_9ACTO (A8WDM7)			2e-40	171	34%	UniProt GenBank	Glycosyltransferase		Streptomyces eurythermus
49	D9VBX2_9ACTO (D9VBX2)			3e-40	171	37%	UniProt GenBank	Putative uncharacterized protein	SSMG_03360	Streptomyces sp. AA4
50	Q9L9F5_STRSH (Q9L9F5)			3e-40	170	35%	UniProt GenBank	NovM	novM	Streptomyces spheroides Streptomyces caeruleus
51	Q5SFB5_STRBI (Q5SFB5)			6e-40	169	33%	UniProt GenBank	Putative chalcose glycosyltransferase	chmCIII	Streptomyces bikiniensis
52	D7B009_NOCDD (D7B009)			6e-40	169	34%	UniProt GenBank	Putative uncharacterized protein	Ndas_4711	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
53	B0LJ53_9ACTO (B0LJ53)			2e-39	168	32%	UniProt GenBank	Lcz36	lcz36	Streptomyces sanglieri
54	B5G890_9ACTO (B5G890)			2e-39	167	32%	UniProt GenBank	Glycosyltransferase family 28 domain-containing protein	SSBG_00498	Streptomyces sp. SPB74
55	D8I4J6_AMYMU (D8I4J6)			2e-39	167	36%	UniProt GenBank	Putative glycosyl transferase	AMED_5410	Amycolatopsis mediterranei (strain U-32)
56	D6AXN2_9ACTO (D6AXN2)			2e-39	167	33%	UniProt GenBank	RdmH	SSHG_05324	Streptomyces albus J1074
57	Q331Q0_9ACTO (Q331Q0)			3e-39	167	33%	UniProt GenBank	Chalcosyltransferase	gerTII	Streptomyces sp. KCTC 0041BP
58	B3TMP7_9ACTO (B3TMP7)			3e-39	167	33%	UniProt GenBank	Glycosyltransferase	KijC3	Actinomadura kijaniata
59	B4VEK6_9ACTO (B4VEK6)			4e-39	167	33%	UniProt GenBank	Chalcosyltransferase	SSAG_06216	Streptomyces sp. Mg1
60	Q9ZGH7_9ACTO (Q9ZGH7)			4e-39	167	33%	UniProt GenBank	Glycosyl transferase	desVII	Streptomyces venezuelae
61	B5G8A2_9ACTO (B5G8A2)			5e-39	166	37%	UniProt GenBank	Glycosyltransferase family 28 domain-containing protein	SSBG_00510	Streptomyces sp. SPB74
62	E8RWS4_MICSL (E8RWS4)			7e-39	166	33%	UniProt GenBank	Putative uncharacterized protein	ML5_4413	Micromonospora sp. (strain L5)
63	D9T2A5_MICAI (D9T2A5)			7e-39	166	33%	UniProt GenBank	Putative uncharacterized protein	Micau_4008	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
64	Q2HR27_9ACTO (Q2HR27)			7e-39	166	34%	UniProt GenBank	Putative O-glycosyltransferase	schS10	Streptomyces sp. SCC 2136
65	Q935Z8_9ACTO (Q935Z8)			7e-39	166	33%	UniProt GenBank	RdmH	rdmH	Streptomyces purpurascens
66	Q194P5_STRAA (Q194P5)			3e-38	164	34%	UniProt GenBank	Glycosyltransferase	mtmGI	Streptomyces argillaceus
67	B5L6J8_MICCH (B5L6J8)			5e-38	163	34%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
68	P95834_STRPE (P95834)			5e-38	163	34%	UniProt GenBank	Putative baumycin biosynthesis protein	dnrH	Streptomyces peucetius
69	C4NYK7_9ACTO (C4NYK7)			6e-38	163	32%	UniProt GenBank	SaqGT1	saqGT1	Micromonospora sp. Tu 6368
70	E1ARK6_STRAU (E1ARK6)			8e-38	162	34%	UniProt GenBank	Putative glycosyltransferase	sa46	Streptomyces aureofaciens
71	Q9L4U6_9ACTO (Q9L4U6)			1e-37	162	35%	UniProt GenBank	Putative glycosyl transferase	aknS	Streptomyces galilaeus
72	Q83X73_STRRO (Q83X73)			2e-37	161	33%	UniProt GenBank	Glycosyltransferase LkmI	lkmI	Streptomyces rochei Streptomyces parvullus
73	A0ACI7_STRAM (A0ACI7)			2e-37	161	33%	UniProt GenBank	Putative glycosyltransferase	SAMR0481	Streptomyces ambofaciens ATCC 23877
74	Q6T1C7_STRGL (Q6T1C7)			3e-37	160	33%	UniProt GenBank	Glycosyltransferase LndGT4		Streptomyces globisporus
75	Q9L555_9ACTO (Q9L555)			3e-37	160	31%	UniProt GenBank	AknK	aknK	Streptomyces galilaeus
76	D9UBQ5_STRPR (D9UBQ5)			3e-37	160	33%	UniProt GenBank	Putative glycosyltransferase	cpp29	Streptomyces pristinaespiralis	2.4.1.- niceE keggE
77	D6X7X2_STRPR (D6X7X2)			3e-37	160	33%	UniProt GenBank	Glycosyltransferase LndGT4	SSDG_07505	Streptomyces pristinaespiralis ATCC 25486
78	B5L6L9_MICCH (B5L6L9)			5e-37	160	33%	UniProt GenBank	Glycosyltransferase		Micromonospora chalcea
79	Q8VWB7_9ACTO (Q8VWB7)			5e-37	160	31%	UniProt GenBank	AclK	aclK	Streptomyces galilaeus
80	Q4JHQ3_9PSEU (Q4JHQ3)			5e-37	160	33%	UniProt GenBank	BusP	busP	Saccharopolyspora pogona
81	Q9F8U7_9ACTO (Q9F8U7)			6e-37	159	35%	UniProt GenBank	Glycosyl transferase	couM	Streptomyces rishiriensis
82	A8Y8I1_STRAM (A8Y8I1)			9e-37	159	30%	UniProt GenBank	Probable glycosyltransferase	srm17	Streptomyces ambofaciens
83	A4FK43_SACEN (A4FK43)			9e-37	159	34%	UniProt GenBank	Putative glycosyl transferase, related to UDP-glucuronosyltransferase	iroB SACE_5174	Saccharopolyspora erythraea (strain NRRL 23338)
84	D1A6T1_THECD (D1A6T1)			1e-36	159	35%	UniProt GenBank	Putative uncharacterized protein	Tcur_2790	Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
85	Q9RN61_STRNO (Q9RN61)			1e-36	159	36%	UniProt GenBank	Putative glycosyl transferase	snogD	Streptomyces nogalater
86	C0JWA3_9ACTO (C0JWA3)			1e-36	159	35%	UniProt GenBank	PokGT1	pokGT1	Streptomyces diastatochromogenes
87	O87830_STRAT (O87830)			1e-36	159	32%	UniProt GenBank	Glycosyltransferase	oleG1	Streptomyces antibioticus
88	D7AZB3_NOCDD (D7AZB3)			1e-36	158	34%	UniProt GenBank	Putative uncharacterized protein	Ndas_4707	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
89	D5UX47_TSUPD (D5UX47)			2e-36	157	33%	UniProt GenBank	Putative uncharacterized protein	Tpau_3487	Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) Corynebacterium paurometabolum
90	D7B025_NOCDD (D7B025)			3e-36	157	33%	UniProt GenBank	Putative uncharacterized protein	Ndas_4727	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
91	A4GV89_9ACTO (A4GV89)			3e-36	157	33%	UniProt GenBank	Glycosyltransferase	holN	Streptomyces sp. FU107
92	Q194P6_STRAA (Q194P6)			4e-36	157	35%	UniProt GenBank	Glycosyltransferase	mtmGII	Streptomyces argillaceus
93	E1ARJ9_STRAU (E1ARJ9)			5e-36	156	33%	UniProt GenBank	Putative glycosyltransferase	sa53	Streptomyces aureofaciens
94	D9T2A9_MICAI (D9T2A9)			7e-36	156	31%	UniProt GenBank	Putative uncharacterized protein	Micau_4012	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
95	Q0H2X6_9ACTO (Q0H2X6)			1e-35	155	32%	UniProt GenBank	Putative O-glycosyltransferase	atG1	Actinomadura melliaura
96	D8I4J7_AMYMU (D8I4J7)			1e-35	155	33%	UniProt GenBank	Putative glycosyl transferase	AMED_5411	Amycolatopsis mediterranei (strain U-32)
97	E8RWS0_MICSL (E8RWS0)			2e-35	155	32%	UniProt GenBank	Putative uncharacterized protein	ML5_4409	Micromonospora sp. (strain L5)
98	A7DWJ3_STRTE (A7DWJ3)			2e-35	154	36%	UniProt GenBank	Putative inactive gylcosyltransferase	llpG	Streptomyces tendae
99	Q9ALN7_9PSEU (Q9ALN7)			2e-35	154	31%	UniProt GenBank	Probable NDP-forosamyltransferase	spnP	Saccharopolyspora spinosa
100	A4FFB3_SACEN (A4FFB3)			2e-35	154	36%	UniProt GenBank	Putative uncharacterized protein	SACE_3464	Saccharopolyspora erythraea (strain NRRL 23338)

	accession	DB	alignment	Evalue	Score	Ident.	link	information	pubmed
1	Q9RP99_STRFR (Q9RP99)			0.0	763	100%	UniProt GenBank	Product Glycosyl transferase Gene urdGT1c Organism Streptomyces fradiae Streptomyces roseoflavus	1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
2	Q9RPA1_STRFR (Q9RPA1)			0.0	673	92%	UniProt GenBank	Product Glycosyl transferase Gene urdGT1b Organism Streptomyces fradiae Streptomyces roseoflavus	1uniprot[Pubmed] 10658661 [Medline] 20121748 Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
3	Q2HR28_9ACTO (Q2HR28)			1e-122	442	59%	UniProt GenBank	Product Putative O-glycosyltransferase Gene schS9 Organism Streptomyces sp. SCC 2136	1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
4	D7BZS3_STRBB (D7BZS3)			1e-119	434	60%	UniProt GenBank	Product Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B Gene SBI_06858 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
5	C4NYL1_9ACTO (C4NYL1)			1e-113	414	59%	UniProt GenBank	Product SaqGT4 Gene saqGT4 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
6	A4GV88_9ACTO (A4GV88)			1e-109	400	55%	UniProt GenBank	Product Glycosyltransferase Gene holL Organism Streptomyces sp. Tu1156	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
7	C4NYL0_9ACTO (C4NYL0)			1e-107	392	56%	UniProt GenBank	Product SaqGT3 Gene saqGT3 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
8	Q9ZGB8_STRCY (Q9ZGB8)			1e-107	392	55%	UniProt GenBank	Product Glycosyl transferase homolog Gene lanGT1 Organism Streptomyces cyanogenus	1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
9	D7BZS5_STRBB (D7BZS5)			2e-99	367	53%	UniProt GenBank	Product IroB Gene SBI_06860 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
10	A4GV86_9ACTO (A4GV86)			2e-96	357	52%	UniProt GenBank	Product Glycosyltransferase Gene holA Organism Streptomyces sp. FU107	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
11	Q6QR18_STRGL (Q6QR18)			5e-96	356	54%	UniProt GenBank	Product Glycosyl transferase Gene   Organism Streptomyces globisporus	1uniprot[Pubmed] 15123249 Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004]
12	Q9ZGB4_STRCY (Q9ZGB4)			2e-91	341	52%	UniProt GenBank	Product Glycosyl transferase homolog Gene lanGT3 Organism Streptomyces cyanogenus	1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
14	Q4JHR2_9PSEU (Q4JHR2)			3e-57	227	37%	UniProt GenBank	Product BusG Gene busG Organism Saccharopolyspora pogona	1uniprot[Pubmed] 16179985 Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
15	Q9ALM8_9PSEU (Q9ALM8)			9e-56	222	36%	UniProt GenBank	Product Probable NDP-rhamnosyltransferase Gene spnG Organism Saccharopolyspora spinosa	1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
16	D7BZR2_STRBB (D7BZR2)			2e-54	217	38%	UniProt GenBank	Product Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B Gene SBI_06847 Organism Streptomyces bingchenggensis (strain BCW-1)	1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
17	C0JWA0_9ACTO (C0JWA0)			2e-51	208	38%	UniProt GenBank	Product PokGT2 Gene pokGT2 Organism Streptomyces diastatochromogenes	1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
18	D8I4K0_AMYMU (D8I4K0)			3e-51	207	37%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5414 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
21	D8I4K4_AMYMU (D8I4K4)			1e-47	195	35%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5418 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
22	Q4R0L9_STRCX (Q4R0L9)			2e-47	194	36%	UniProt GenBank	Product ChaGT1 protein Gene chaGT1 Organism Streptomyces chartreusis	1uniprot[Pubmed] 15911378 Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
24	Q194P9_STRAA (Q194P9)			3e-45	187	35%	UniProt GenBank	Product Glycosyltransferase Gene mtmGIII Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
26	O87831_STRAT (O87831)			3e-45	187	34%	UniProt GenBank	Product Glycosyltransferase Gene oleG2 Organism Streptomyces antibioticus	1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998]
29	Q0R4N0_STRAT (Q0R4N0)			1e-43	182	37%	UniProt GenBank	Product ChlC6 Gene   Organism Streptomyces antibioticus	1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
30	Q0R4P9_STRAT (Q0R4P9)			1e-43	182	35%	UniProt GenBank	Product ChlC7 Gene   Organism Streptomyces antibioticus	1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
31	D2AY79_STRRD (D2AY79)			3e-43	181	39%	UniProt GenBank	Product IroB Gene Sros_4185 Organism Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)	1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
32	Q76KZ6_STRHA (Q76KZ6)			3e-43	181	33%	UniProt GenBank	Product Glycosyltransferase Gene vinC Organism Streptomyces halstedii	1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
34	Q8GHC2_9ACTO (Q8GHC2)			5e-43	180	36%	UniProt GenBank	Product Glycosyltransferase Gene cloM Organism Streptomyces roseochromogenes subsp. oscitans	1uniprot[Pubmed] 12480894 [Medline] 22368916 Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002]
35	B3TMP5_9ACTO (B3TMP5)			5e-43	179	35%	UniProt GenBank	Product Glycosyltransferase Gene KijC1 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
36	B3TMN6_9ACTO (B3TMN6)			3e-42	177	33%	UniProt GenBank	Product Glycosyltransferase Gene KijA4 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
37	B5L6L8_MICCH (B5L6L8)			3e-42	177	31%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
38	Q194Q0_STRAA (Q194Q0)			4e-42	177	35%	UniProt GenBank	Product Glycosyltransferase Gene mtmGIV Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
39	D4QF41_9ACTO (D4QF41)			6e-42	176	36%	UniProt GenBank	Product Rhamnosyltransferase Gene lipB1 Organism Streptomyces sp. SANK 60405	1uniprot[Pubmed] 20043306 The biosynthesis of liposidomycin-like A-90289 antibiotics featuring a new type of sulfotransferase.(Chembiochem) [2010]
40	Q9RN63_STRNO (Q9RN63)			1e-41	175	35%	UniProt GenBank	Product Putative glycosyl transferase Gene snogE Organism Streptomyces nogalater	1uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] 2uniprot[Pubmed] 10639368 [Medline] 20106987 Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000] [pubmed all]
41	D8I4I4_AMYMU (D8I4I4)			1e-41	175	35%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5398 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
42	Q2P9Y9_9ACTO (Q2P9Y9)			2e-41	174	34%	UniProt GenBank	Product Glycosyl transferase Gene stfG Organism Streptomyces steffisburgensis	1uniprot[Pubmed] 16751529 Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
44	Q54824_STRPE (Q54824)			2e-41	174	35%	UniProt GenBank	Product Glycosyl transferase Gene dnrS Organism Streptomyces peucetius	1uniprot[Pubmed] 7592454 [Medline] 96062261 Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis.(J. Bacteriol.) [1995]
45	D8I4J9_AMYMU (D8I4J9)			8e-41	172	37%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5413 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
46	Q83WE1_MICGR (Q83WE1)			1e-40	172	34%	UniProt GenBank	Product Glycosyltransferase Gene mycB Organism Micromonospora griseorubida	1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
47	A4GV85_9ACTO (A4GV85)			1e-40	172	36%	UniProt GenBank	Product Glycosyltransferase Gene holC Organism Streptomyces rufochromogenes	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
50	Q9L9F5_STRSH (Q9L9F5)			3e-40	170	35%	UniProt GenBank	Product NovM Gene novM Organism Streptomyces spheroides Streptomyces caeruleus	1uniprot[Pubmed] 10770754 [Medline] 20233587 Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000]
51	Q5SFB5_STRBI (Q5SFB5)			6e-40	169	33%	UniProt GenBank	Product Putative chalcose glycosyltransferase Gene chmCIII Organism Streptomyces bikiniensis	1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
52	D7B009_NOCDD (D7B009)			6e-40	169	34%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4711 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
53	B0LJ53_9ACTO (B0LJ53)			2e-39	168	32%	UniProt GenBank	Product Lcz36 Gene lcz36 Organism Streptomyces sanglieri	1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
55	D8I4J6_AMYMU (D8I4J6)			2e-39	167	36%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5410 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
57	Q331Q0_9ACTO (Q331Q0)			3e-39	167	33%	UniProt GenBank	Product Chalcosyltransferase Gene gerTII Organism Streptomyces sp. KCTC 0041BP	1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
58	B3TMP7_9ACTO (B3TMP7)			3e-39	167	33%	UniProt GenBank	Product Glycosyltransferase Gene KijC3 Organism Actinomadura kijaniata	1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
60	Q9ZGH7_9ACTO (Q9ZGH7)			4e-39	167	33%	UniProt GenBank	Product Glycosyl transferase Gene desVII Organism Streptomyces venezuelae	1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
64	Q2HR27_9ACTO (Q2HR27)			7e-39	166	34%	UniProt GenBank	Product Putative O-glycosyltransferase Gene schS10 Organism Streptomyces sp. SCC 2136	1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
66	Q194P5_STRAA (Q194P5)			3e-38	164	34%	UniProt GenBank	Product Glycosyltransferase Gene mtmGI Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
67	B5L6J8_MICCH (B5L6J8)			5e-38	163	34%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
68	P95834_STRPE (P95834)			5e-38	163	34%	UniProt GenBank	Product Putative baumycin biosynthesis protein Gene dnrH Organism Streptomyces peucetius	1uniprot[Pubmed] 8955419 [Medline] 97113559 Enhanced antibiotic production by manipulation of the Streptomyces peucetius dnrH and dnmT genes involved in doxorubicin (adriamycin) biosynthesis.(J. Bacteriol.) [1996] 2uniprot[Pubmed] 9864344 [Medline] 99084971 Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene.(J. Bacteriol.) [1999] [pubmed all]
69	C4NYK7_9ACTO (C4NYK7)			6e-38	163	32%	UniProt GenBank	Product SaqGT1 Gene saqGT1 Organism Micromonospora sp. Tu 6368	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] [pubmed all]
70	E1ARK6_STRAU (E1ARK6)			8e-38	162	34%	UniProt GenBank	Product Putative glycosyltransferase Gene sa46 Organism Streptomyces aureofaciens	1uniprot[Pubmed] 21393365 The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
71	Q9L4U6_9ACTO (Q9L4U6)			1e-37	162	35%	UniProt GenBank	Product Putative glycosyl transferase Gene aknS Organism Streptomyces galilaeus	1uniprot[Pubmed] 11016846 [Medline] 20469061 A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000]
72	Q83X73_STRRO (Q83X73)			2e-37	161	33%	UniProt GenBank	Product Glycosyltransferase LkmI Gene lkmI Organism Streptomyces rochei Streptomyces parvullus	1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] [pubmed all]
73	A0ACI7_STRAM (A0ACI7)			2e-37	161	33%	UniProt GenBank	Product Putative glycosyltransferase Gene SAMR0481 Organism Streptomyces ambofaciens ATCC 23877	1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
74	Q6T1C7_STRGL (Q6T1C7)			3e-37	160	33%	UniProt GenBank	Product Glycosyltransferase LndGT4 Gene   Organism Streptomyces globisporus	1uniprot[Pubmed] 15123249 Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.(Chem. Biol.) [2004]
75	Q9L555_9ACTO (Q9L555)			3e-37	160	31%	UniProt GenBank	Product AknK Gene aknK Organism Streptomyces galilaeus	1uniprot[Pubmed] 12137949 [Medline] 22133312 Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
76	D9UBQ5_STRPR (D9UBQ5)			3e-37	160	33%	UniProt GenBank	Product Putative glycosyltransferase Gene cpp29 Organism Streptomyces pristinaespiralis	1uniprot[Pubmed] 21342465 Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
78	B5L6L9_MICCH (B5L6L9)			5e-37	160	33%	UniProt GenBank	Product Glycosyltransferase Gene   Organism Micromonospora chalcea	1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
79	Q8VWB7_9ACTO (Q8VWB7)			5e-37	160	31%	UniProt GenBank	Product AclK Gene aclK Organism Streptomyces galilaeus	1uniprot[Pubmed] 12399480 [Medline] 22286521 Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
80	Q4JHQ3_9PSEU (Q4JHQ3)			5e-37	160	33%	UniProt GenBank	Product BusP Gene busP Organism Saccharopolyspora pogona	1uniprot[Pubmed] 16179985 Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
81	Q9F8U7_9ACTO (Q9F8U7)			6e-37	159	35%	UniProt GenBank	Product Glycosyl transferase Gene couM Organism Streptomyces rishiriensis	1uniprot[Pubmed] 11036020 [Medline] 20493109 Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000]
82	A8Y8I1_STRAM (A8Y8I1)			9e-37	159	30%	UniProt GenBank	Product Probable glycosyltransferase Gene srm17 Organism Streptomyces ambofaciens	1uniprot Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007]
83	A4FK43_SACEN (A4FK43)			9e-37	159	34%	UniProt GenBank	Product Putative glycosyl transferase, related to UDP-glucuronosyltransferase Gene iroB SACE_5174 Organism Saccharopolyspora erythraea (strain NRRL 23338)	1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
84	D1A6T1_THECD (D1A6T1)			1e-36	159	35%	UniProt GenBank	Product Putative uncharacterized protein Gene Tcur_2790 Organism Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)	1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
85	Q9RN61_STRNO (Q9RN61)			1e-36	159	36%	UniProt GenBank	Product Putative glycosyl transferase Gene snogD Organism Streptomyces nogalater	1uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] 2uniprot[Pubmed] 10639368 [Medline] 20106987 Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000] [pubmed all]
86	C0JWA3_9ACTO (C0JWA3)			1e-36	159	35%	UniProt GenBank	Product PokGT1 Gene pokGT1 Organism Streptomyces diastatochromogenes	1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
87	O87830_STRAT (O87830)			1e-36	159	32%	UniProt GenBank	Product Glycosyltransferase Gene oleG1 Organism Streptomyces antibioticus	1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998]
88	D7AZB3_NOCDD (D7AZB3)			1e-36	158	34%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4707 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
90	D7B025_NOCDD (D7B025)			3e-36	157	33%	UniProt GenBank	Product Putative uncharacterized protein Gene Ndas_4727 Organism Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei	1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
91	A4GV89_9ACTO (A4GV89)			3e-36	157	33%	UniProt GenBank	Product Glycosyltransferase Gene holN Organism Streptomyces sp. FU107	1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
92	Q194P6_STRAA (Q194P6)			4e-36	157	35%	UniProt GenBank	Product Glycosyltransferase Gene mtmGII Organism Streptomyces argillaceus	1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] [pubmed all]
93	E1ARJ9_STRAU (E1ARJ9)			5e-36	156	33%	UniProt GenBank	Product Putative glycosyltransferase Gene sa53 Organism Streptomyces aureofaciens	1uniprot[Pubmed] 21393365 The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
95	Q0H2X6_9ACTO (Q0H2X6)			1e-35	155	32%	UniProt GenBank	Product Putative O-glycosyltransferase Gene atG1 Organism Actinomadura melliaura	1uniprot[Pubmed] 16873021 Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]
96	D8I4J7_AMYMU (D8I4J7)			1e-35	155	33%	UniProt GenBank	Product Putative glycosyl transferase Gene AMED_5411 Organism Amycolatopsis mediterranei (strain U-32)	1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
98	A7DWJ3_STRTE (A7DWJ3)			2e-35	154	36%	UniProt GenBank	Product Putative inactive gylcosyltransferase Gene llpG Organism Streptomyces tendae	1uniprot Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010]
99	Q9ALN7_9PSEU (Q9ALN7)			2e-35	154	31%	UniProt GenBank	Product Probable NDP-forosamyltransferase Gene spnP Organism Saccharopolyspora spinosa	1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
100	A4FFB3_SACEN (A4FFB3)			2e-35	154	36%	UniProt GenBank	Product Putative uncharacterized protein Gene SACE_3464 Organism Saccharopolyspora erythraea (strain NRRL 23338)	1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]