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遺伝子 : Glutamine amidotransferase subunit PdxT (PDXT)

遺伝子情報

ID NRULE_0207
遺伝子ID PDXT
作成日 2013/05/09
タンパク質名
Protein name
Full
Glutamine amidotransferase subunit PdxT
EC
EC 2.6.-.-
Synonym
Full
Glutamine amidotransferase glutaminase subunit PdxT
遺伝子名 pdxT
遺伝子条件 HAMAP; MF_01615; hit=1
参照
Gene Ontology
GO
GO:0016740, F:transferase activity, IEA:HAMAP
GO:0006543, P:glutamine catabolic process, IEA:HAMAP
GO:0042823, P:pyridoxal phosphate biosynthetic process, IEA:HAMAP
Phylogenomic databases
eggNOG
COG0311, -
HOGENOM
HOG000039949, -
KO
K08681, -
ProtClustDB
PRK13525, -
Enzyme and pathway databases
BioCyc
MetaCyc:MONOMER-15503, -
UniPathway
UPA00245, -
Family and domain databases
HAMAP
MF_01615, PdxT, 1, -
InterPro
IPR002161, Glutamine_amidoTferase_suPdxT
IPR021196, PdxT/SNO_CS
Pfam
PF01174, SNO, 1
PIRSF
PIRSF005639, Glut_amidoT_SNO, 1
TIGRFAMs
TIGR03800, PLP_synth_Pdx2, 1
PROSITE
PS01236, PDXT_SNO_1, 1
PS51130, PDXT_SNO_2, 1
配列の特徴
P37528 Bacillus subtilis (strain 168).
ACT_SITE79Nucleophile.
ACT_SITE170 
ACT_SITE172 
BINDING106Glutamine (Potential).
注釈
Function
Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS
Pathway
Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis
Subunit structure
Forms a complex with PdxS
Sequence similarities
Belongs to the glutamine amidotransferase PdxT/SNO family
参考文献
P37528 Bacillus subtilis (strain 168).
7584024
Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin. (DNA Res. 1994)
9384377
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. (Nature. 1997)
14762015
Physical and enzymological interaction of Bacillus subtilis proteins required for de novo pyridoxal 5'-phosphate biosynthesis. (J Bacteriol. 2004)



関与する機能

機能名
Vitamin B6 biosynthesis (PdxS/PdxT pathway)

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acaricomes phytoseiuli107788C501_11195hypothetical protein
Acidimicrobium ferrooxidans103882Afer_1220SNO glutamine amidotransferase
Acidiphilium multivorum100883ACMV_P3_00460glutamine amidotransferase subunit PdxT
Acidobacterium capsulatum15755ACP_0458glutamine amidotransferase, SNO family
Actinoalloteichus cyanogriseus14455G443_17_01090glutamine amidotransferase involved in pyridoxine biosynthesis
Actinoalloteichus spitiensis102582ACTIDRAF_11945hypothetical protein
Actinomadura atramentaria14695G339_28385hypothetical protein
Actinoplanes missouriensis102363AMIS_62850putative glutamine amidotransferase
Actinopolyspora iraqiensis103187ACTIR_684_00030glutamine amidotransferase involved in pyridoxine biosynthesis
Actinosynnema mirum14064Amir_2109SNO glutamine amidotransferase
Aeropyrum pernix100138APE_0244.1pyridoxal 5'-phosphate biosynthesis protein
Alicyclobacillus acidocaldarius subsp. acidocaldarius15652Aaci_0013SNO glutamine amidotransferase
Amycolatopsis azurea14573C791_3964Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit
Amycolatopsis mediterranei13415RAM_27025glutamine amidotransferase involved in pyridoxine biosynthesis
Anaerolinea thermophila100420ANT_01660glutamine amidotransferase subunit PdxT
Anoxybacillus flavithermus15317Aflv_0012Pyridoxine biosynthesis enzyme PDX1/PDX2, glutaminase subunit
Archaeoglobus profundus100127Arcpr_0681SNO glutamine amidotransferase
Ardenticatena maritimaARMA_06165'-phosphate synthase pdxT subunit
Arthrobacter globiformis12137ARGLB_039_00190glutamine amidotransferase subunit PdxT
Austwickia chelonae105200AUCHE_05_04150glutamine amidotransferase subunit PdxT
Bacillus amyloliquefaciens15535BAMF_0012glutamine amidotransferase, SNO family
Bacillus atrophaeus13721BATRMS_03_00120glutamine amidotransferase subunit PdxT
Bacillus cereus15305BC_0016pyridoxine biosynthesis amidotransferase
Bacillus licheniformis12200BL02354SNO glutamine amidotransferase
Bacillus licheniformis12195BLi00017pyridoxal-5'-phosphate synthase glutaminase subunit PdxT
Bacillus mojavensis15718GYU_05_00060glutamine amidotransferase subunit PdxT
Bacillus mycoides101228bmyco0001_50Glutamine amidotransferase subunit pdxT
Bacillus pseudomycoides101232bpmyx0001_50Glutamine amidotransferase subunit pdxT
Bacillus psychrosaccharolyticus101233WYK_221_00380glutamine amidotransferase subunit PdxT
Bacillus pumilus12092BAT_4146glutamine amidotransferase subunit PdxT (Glutamineamidotransferase glutaminase subunit pdxT)
Bacillus subtilis3134BSU6633_17731glutamine amidotransferase subunit PdxT
Bacillus subtilis subsp. subtilis13719BSU00120glutamine amidotransferase for pyridoxal phosphate synthesis; pyridoxal 5'-phosphate synthase complex, Glutamine amidotransferase subunit PdxT
Bacillus thuringiensis101235bthur0008_50Glutamine amidotransferase subunit pdxT
Bacillus vallismortis101236BvalD_010100013849glutamine amidotransferase subunit PdxT
Beutenbergia cavernae16432Bcav_1988SNO glutamine amidotransferase
Brevibacillus brevis100599BBR47_00170glutamine amidotransferase subunit PdxT
Brevibacterium linens12170BlinB_010200017701glutamine amidotransferase subunit PdxT
Caldanaerobacter subterraneus subsp. tengcongensis100824TTE0822predicted glutamine amidotransferase involved in pyridoxine biosynthesis
Caldilinea aerophila104270CLDAP_15420putative glutamine amidotransferase subunit PdxT
Caldisericum exile104410CSE_10830glutamine amidotransferase subunit PdxT
Candidatus Korarchaeum cryptofilumKcr_0775SNO glutamine amidotransferase
Candidatus Nitrosopumilus sp.NSED_08150SNO glutamine amidotransferase
Candidatus Solibacter usitatusAcid_0289SNO glutamine amidotransferase
Catenulispora acidiphila102108Caci_2350SNO glutamine amidotransferase
Cellulomonas fimi15513Celf_2033SNO glutamine amidotransferase
Cellulomonas flavigena3775Cfla_1792SNO glutamine amidotransferase
Cenarchaeum symbiosumCENSYa_0065pyridoxine biosynthesis protein/glutamine amidotransferase
Chloracidobacterium thermophilum BCabther_A2189pyridoxal phosphate synthase yaaE subunit
Chthonomonas calidiroseaCCALI_00268pyridoxal phosphate synthase yaaE subunit
Clostridium acetobutylicum13948CA_C0595Glutamine amidotranspherase (possibly involved in histidine and purine biosinthesis)
Clostridium kluyveri12016CKR_2129hypothetical protein
Conexibacter woesei100937Cwoe_3161SNO glutamine amidotransferase
Corynebacterium callunae15359H924_03590glutamine amidotransferase subunit PdxT
Corynebacterium glutamicum12168Cgl0789Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
Corynebacterium striatum15291HMPREF0308_1602pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2
Corynebacterium terpenotabidum14764A606_06150amidotransferase involved in pyridoxine biosynthesis
Dehalococcoides mccartyiDehaBAV1_0573pyridoxal phosphate synthase yaaE subunit
Deinococcus proteolyticus101906Deipr_0166Glutamine amidotransferase subunit pdxT
Dictyoglomus turgidumDtur_1483SNO glutamine amidotransferase
Fibrobacter succinogenesFisuc_0270SNO glutamine amidotransferase
Fimbriimonas ginsengisoliOP10G_2432SNO glutamine amidotransferase
Geodermatophilus obscurus13315Gobs_3180SNO glutamine amidotransferase
Gordonia aichiensis108223GOACH_05_01370glutamine amidotransferase subunit PdxT
Gordonia alkanivorans16433GOALK_014_00300glutamine amidotransferase subunit PdxT
Gordonia amarae15530GOAMR_19_00330glutamine amidotransferase subunit PdxT
Gordonia amicalis100051GOAMI_17_01230glutamine amidotransferase subunit PdxT
Gordonia araii100433GOARA_064_00940glutamine amidotransferase subunit PdxT
Gordonia bronchialis16047Gbro_2298SNO glutamine amidotransferase
Gordonia effusa100432GOEFS_050_00480glutamine amidotransferase subunit PdxT
Gordonia hirsuta16056GOHSU_18_01190glutamine amidotransferase subunit PdxT
Gordonia namibiensis108229GONAM_14_00110glutamine amidotransferase subunit PdxT
Gordonia otitidis100426GOOTI_135_00120glutamine amidotransferase subunit PdxT
Gordonia polyisoprenivorans16320GOPIP_056_00210glutamine amidotransferase subunit PdxT
Gordonia rhizosphera16068GORHZ_192_00110glutamine amidotransferase subunit PdxT
Gordonia rubripertincta101908GORBP_053_00440glutamine amidotransferase subunit PdxT
Gordonia sihwensis108236GSI01S_48_00110glutamine amidotransferase subunit PdxT
Gordonia soli108243GS4_19_00300glutamine amidotransferase subunit PdxT
Gordonia sputi100414GOSPT_064_00020glutamine amidotransferase subunit PdxT
Gordonia terrae100016GOTRE_006_00230glutamine amidotransferase subunit PdxT
Haloarcula vallismortis14741C437_03067glutamine amidotransferase subunit PdxT
Halobacillus halophilus102448HBHAL_1014glutamine amidotransferase subunit PdxT
Halobacterium sp.VNG_2598Gimidazoleglycerol-phosphate synthase
Haloplasma contractileHLPCO_001512Glutamine amidotransferase subunit PdxT protein
Herpetosiphon aurantiacusHaur_3807SNO glutamine amidotransferase
Intrasporangium calvum12989Intca_1859pyridoxal phosphate synthase yaaE subunit
Jonesia denitrificans15587Jden_1601SNO glutamine amidotransferase
Kineococcus radiotolerans101839Krad_3058SNO glutamine amidotransferase
Kineosphaera limosa100340KILIM_011_00740glutamine amidotransferase subunit PdxT
Kitasatospora setae14216KSE_14470putative glutamine amidotransferase subunit PdxT
Kocuria rhizophila103217KRH_01120pyridoxal phosphate synthase component Pdx2
Kribbella flavida14399Kfla_4409SNO glutamine amidotransferase
Ktedonobacter racemiferKrac_9162SNO glutamine amidotransferase
Kyrpidia tusciae15312Btus_0013SNO glutamine amidotransferase
Kytococcus sedentarius15357Ksed_15360pyridoxal phosphate synthase yaaE subunit
Leuconostoc lactis107866EY7_342_00010Glutamine amidotransferase subunit PdxT
EY7_958_00020Glutamine amidotransferase subunit PdxT
Limnochorda pilosa110152LIP_1093glutamine amidotransferase
Meiothermus ruber106122Mrub_1547SNO glutamine amidotransferase
Meiothermus silvanus106475Mesil_2041SNO glutamine amidotransferase
Methanocaldococcus jannaschii100440MJ_1661conserved hypothetical protein
Methanocella paludicola101707MCP_1664glutamine amidotransferase subunit PdxT
Methanococcus maripaludis101832MMP1656putative pyridoxine biosynthetic glutamine amidotransferase
Methanococcus maripaludisMmarC5_1753pyridoxal phosphate synthase yaaE subunit
Methanopyrus kandleriMK1062Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
Micrococcus luteus3333Mlut_19920pyridoxal phosphate synthase yaaE subunit
Microlunatus phosphovorus101784MLP_26660glutamine amidotransferase subunit PdxT
Micromonospora aurantiaca16155Micau_2260SNO glutamine amidotransferase
Mobilicoccus pelagius104925MOPEL_021_00560glutamine amidotransferase subunit PdxT
Nakamurella multipartita105858Namu_3399SNO glutamine amidotransferase
Nitriliruptor alkaliphilusNitalDRAFT_3334pyridoxal phosphate synthase yaaE subunit
Nitrososphaera viennensisNVIE_029420glutamine amidotransferase subunit PdxT
Nocardiopsis dassonvillei14626Ndas_0824SNO glutamine amidotransferase
Oceanithermus profundus100410Ocepr_1142pyridoxal phosphate synthase yaaE subunit
Paenibacillus alvei3343PAV_2c06740glutamine amidotransferase subunit PdxT
Paenibacillus peoriae15541PpeoK3_010100009308hypothetical protein
Paenibacillus polymyxa15309PPT_00475glutamine amidotransferase
Picrophilus torridus100828PTO0504pyridoxine biosynthesis amidotransferase
Propionibacterium acidipropionici12425PACID_18620Glutamine amidotransferase subunit pdxT
Propionibacterium avidum15671HMPREF9153_1994glutamine amidotransferase subunit PdxT
Pyrococcus horikoshii100139PH1354pyridoxal 5'-phosphate biosynthesis protein
Renibacterium salmoninarum15589RSal33209_2003pyridoxine biosynthesis amidotransferase
Rhodococcus erythropolis100887RER_29150probable pyridoxal phosphate synthase component Pdx2
Rhodococcus opacus108011ROP_68670pyridoxal phosphate synthase component Pdx2
Rothia dentocariosa12531HMPREF0733_11098pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2
Rothia mucilaginosa15673ROTMU0001_0233pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2
Rubrobacter xylanophilus100952Rxyl_1317SNO glutamine amidotransferase
Saccharomonospora azurea14651SacazDRAFT_04511pyridoxal 5''-phosphate synthase, glutaminase subunit Pdx2
Saccharomonospora cyanea14841SaccyDRAFT_1866pyridoxal 5''-phosphate synthase, glutaminase subunit Pdx2
Saccharopolyspora erythraea13426SACE_2017SNO glutamine amidotransferase
Saccharopolyspora spinosa15153SspiN1_010100027424glutamine amidotransferase
Saccharothrix espanaensis15066BN6_30670Glutamine amidotransferase subunit pdxT
Salinispora tropica105044Strop_1791SNO glutamine amidotransferase
Selenomonas ruminantium subsp. lactilytica103574SELR_00900putative glutamine amidotransferase subunit PdxT
Sporichthya polymorpha12702Spopo_31_16230Glutamine amidotransferase subunit PdxT
Stackebrandtia nassauensis102104Snas_2628SNO glutamine amidotransferase
Staphylococcus epidermidis12993SE_2261conserved hypothetical protein
Staphylococcus saprophyticus subsp. saprophyticus102446SSP2236putative glutamine amidotransferase family protein
Streptococcus equinus12553HMPREF0819_0561pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2
Streptococcus mitis106071SM12261_0227SNO glutamine amidotransferase family superfamily
Streptomyces avermitilis14893SAV6831putative glutamine amidotransferase
Streptomyces cattleya14057SCAT_5301glutamine amidotransferase for pyridoxal phosphate synthesis
Streptomyces clavuligerus13307SCLAV_0753Glutamine amidotransferase subunit pdxT
Streptomyces ghanaensis15414SSFG_05855glutamine amidotransferase subunit pdxT
Streptomyces mobaraensis13819H340_09460glutamine amidotransferase subunit PdxT
Streptomyces pristinaespiralis13074SSDG_04339glutamine amidotransferase subunit pdxT
Streptomyces purpureus13925STRPU_03_01520Glutamine amidotransferase subunit PdxT
Streptomyces sviceus13980SSEG_05032glutamine amidotransferase subunit pdxT
Streptomyces venezuelae13096SVEN_1122Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit
Streptosporangium roseum3776Sros_6117SNO glutamine amidotransferase family
Sulfolobus tokodaii100140STK_14420pyridoxal 5'-phosphate biosynthesis protein PdxT
Thermobispora bispora14880Tbis_2067SNO glutamine amidotransferase
Thermococcus sp.GQS_05820glutamine amidotransferase subunit PdxT
Thermomicrobium roseumtrd_0025glutamine amidotransferase subunit pdxT
Thermomonospora curvata15933Tcur_2107SNO glutamine amidotransferase
Thermoproteus neutrophilus100436Tneu_0268SNO glutamine amidotransferase
Thermotoga lettingae107922Tlet_1770SNO glutamine amidotransferase
Thermotoga maritima100826TM_0472amidotransferase, putative
Thermotoga naphthophila104846Tnap_0254SNO glutamine amidotransferase
Thermotoga neapolitana107923CTN_0200Glutamine amidotransferase subunit pdxT
Thermotoga petrophila104847Tpet_0448SNO glutamine amidotransferase
Thermotoga thermarum107925Theth_1831pyridoxal phosphate synthase yaaE subunit
Thermus thermophilus101084TTHA0707glutamine amidotransferase (pyridoxine biosynthesis)
Thermus thermophilus101085TT_C0355pyridoxine biosynthesis amidotransferase
Tsukamurella paurometabola16120Tpau_1930SNO glutamine amidotransferase
Xylanimonas cellulosilytica107835Xcel_1664SNO glutamine amidotransferase
Zimmermannella faecalis15706G328_01000hypothetical protein