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Rule : Dihydroneopterin aldolase (FOLB)

Rule Description

ID NRULE_0158
Rule name FOLB
Created 2013-03-12
Protein name
Protein name
Full
Dihydroneopterin aldolase
Short
DHNA
EC
EC 4.1.2.25
Gene name folB
Rule Trigger PFAM; PF02152; hit=1
Cross Reference
Gene Ontology
GO
GO:0004150, F:dihydroneopterin aldolase activity, IDA:EcoCyc
GO:0046656, P:folic acid biosynthetic process, IEA:UniProtKB-KW
GO:0046654, P:tetrahydrofolate biosynthetic process, IEA:UniProtKB-UniPathway
Phylogenomic databases
eggNOG
COG1539, -
HOGENOM
HOG000217627, -
KO
K01633, -
ProtClustDB
PRK11593, -
Enzyme and pathway databases
UniPathway
UPA00077, UER00154
Family and domain databases
InterPro
IPR006156, Dihydroneopterin_aldolase
IPR006157, FolB_dom
Pfam
PF02152, FolB, 1
SMART
SM00905, FolB, 1
TIGRFAMs
TIGR00525, folB, 1
TIGR00526, folB_dom, 1
Feature Not assigned
General annotation
Function
Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin at appreciable velocity
Catalytic activity
2-amino-4-hydroxy-6-(D-erythro-1,2,3- trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6- hydroxymethyl-7,8-dihydropteridine + glycolaldehyde
Pathway
Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2- amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4
Subunit structure
Homooctamer
Sequence similarities
Belongs to the DHNA family
Reference
P0AC16 Escherichia coli (strain K12).
8389741
Amplification of the bacA gene confers bacitracin resistance to Escherichia coli. (J Bacteriol. 1993)
9278503
The complete genome sequence of Escherichia coli K-12. (Science. 1997)
16738553
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. (Mol Syst Biol. 2006)
9651328
Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase. (J Biol Chem. 1998)



Related Function

Function name
Folate biosynthesis

CDS

Data Download
Scientific name NBRC No. CDS Product name
Acaricomes phytoseiuli107788C501_03660hypothetical protein
Acaryochloris marina102967AM1_4915dihydroneopterin aldolase
Acetobacter aceti14818AaceN1_010100003023dihydroneopterin aldolase
Acetobacter pasteurianus105190APA32_00560Dihydroneopterin aldolase
Acetobacter pasteurianus101655APT_1750dihydroneopterin aldolase
Acetobacter tropicalis101654ATPR_0582dihydroneopterin aldolase
Acidimicrobium ferrooxidans103882Afer_1910dihydroneopterin aldolase
Acidiphilium multivorum100883ACMV_27980dihydroneopterin aldolase family protein
Acidithiobacillus ferrooxidansLferr_0126dihydroneopterin aldolase
Acinetobacter radioresistens102413ACRAD_21_00180dihydroneopterin aldolase
Acinetobacter sp.100985ACT4_025_01190dihydroneopterin aldolase
Actinoalloteichus cyanogriseus14455G443_06_00370dihydroneopterin aldolase
Actinoalloteichus spitiensis102582ACTIDRAF_08720hypothetical protein
Actinomadura atramentaria14695G339_15275hypothetical protein
Actinoplanes missouriensis102363AMIS_77870putative dihydroneopterin aldolase
Actinopolyspora iraqiensis103187ACTIR_001_00010dihydroneopterin aldolase
Actinosynnema mirum14064Amir_0316dihydroneopterin aldolase
Aerococcus viridans12219HMPREF0061_0618dihydroneopterin aldolase
Alicyclobacillus acidocaldarius subsp. acidocaldarius15652Aaci_0965dihydroneopterin aldolase
Alloiococcus otitis15545HMPREF9698_01531dihydroneopterin aldolase
Alteromonas macleodii102226MASE_02975dihydroneopterin aldolase FolB
MASE_06420D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
Amycolatopsis azurea14573C791_0696Dihydroneopterin aldolase
Amycolatopsis mediterranei13415RAM_44870dihydroneopterin aldolase
Anoxybacillus flavithermus15317Aflv_0070Dihydroneopterin aldolase
Aquimarina agarilytica107695AagaZ_020100012579dihydroneopterin aldolase
Arcanobacterium haemolyticum15585Arch_02542-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Ardenticatena maritimaARMA_2124dihydroneopterin aldolase
Arthrobacter globiformis12137ARGLB_032_00360dihydroneopterin aldolase
Austwickia chelonae105200AUCHE_03_01700putative dihydroneopterin aldolase
Azorhizobium caulinodans14845AZC_1812dihydroneopterin aldolase
Bacillus amyloliquefaciens15535BAMF_0078dihydroneopterin aldolase
Bacillus atrophaeus13721BATRMS_24_00550dihydroneopterin aldolase
Bacillus cereus15305BC_0080Dihydroneopterin aldolase
Bacillus licheniformis12200BL00862dihydroneopterin aldolase
Bacillus licheniformis12195BLi00094dihydroneopterin aldolase FolB
Bacillus mojavensis15718GYU_04_02790dihydroneopterin aldolase
Bacillus mycoides101228bmyco0001_600Dihydroneopterin aldolase
Bacillus pseudomycoides101232bpmyx0001_600Dihydroneopterin aldolase
Bacillus psychrosaccharolyticus101233WYK_203_00050dihydroneopterin aldolase
Bacillus pumilus12092BAT_4071dihydroneopterin aldolase
Bacillus subtilis3134BSU6633_00665dihydroneopterin aldolase
Bacillus subtilis subsp. subtilis13719BSU00780dihydroneopterin aldolase
Bacillus thuringiensis101235bthur0008_620Dihydroneopterin aldolase
Bacteroides vulgatus14291BVU_0005dihydroneopterin aldolase
Balneola vulgarisB155_RS0112110dihydroneopterin aldolase
Bergeyella zoohelcum16014HMPREF9699_02079dihydroneopterin aldolase
Beutenbergia cavernae16432Bcav_07052-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
Bradyrhizobium diazoefficiens14792bll3058probable dihydroneopterin aldolase (EC 4.1.2.25)
Brevibacillus brevis100599BBR47_01770dihydroneopterin aldolase
Brevibacterium linens12170BlinB_010200013913Dihydroneopterin aldolase
Brevundimonas diminuta12697BDIM_24630dihydroneopterin aldolase
Brevundimonas subvibrioides16000Bresu_0919dihydroneopterin aldolase
Bresu_2112dihydroneopterin aldolase
Caldilinea aerophila104270CLDAP_28290dihydroneopterin aldolase
Catenulispora acidiphila102108Caci_8421dihydroneopterin aldolase
Caulobacter segnis15250Cseg_0578dihydroneopterin aldolase
Cellulomonas fimi15513Celf_05622-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Cellulomonas flavigena3775Cfla_06302-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
Cellulophaga lytica14961Celly_1317dihydroneopterin aldolase
Chitinophaga pinensis15968Cpin_6235dihydroneopterin aldolase
Chlamydia trachomatisCTL0878dihydroneopterin aldolase
Chlorobaculum tepidum103806CT1937dihydroneopterin aldolase
Chlorobium limicola103803Clim_2140dihydroneopterin aldolase
Chromobacterium violaceum12614CV_3689dihydroneopterin aldolase
Chryseobacterium gleum15054HMPREF0204_11918dihydroneopterin aldolase
Chthoniobacter flavusCfE428DRAFT_2402dihydroneopterin aldolase
Chthonomonas calidiroseaCCALI_01931dihydroneopterin aldolase
Clostridium acetobutylicum13948CA_C2927dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein
Clostridium clariflavum101661Clocl_4042dihydroneopterin aldolase
Clostridium kluyveri12016CKR_0868hypothetical protein
Clostridium thermocellum103400Cthe_2582dihydroneopterin aldolase
Conexibacter woesei100937Cwoe_1675dihydroneopterin aldolase
Congregibacter litoralis104960KT71_02237dihydroneopterin aldolase
Coraliomargarita akajimensisCaka_2396dihydroneopterin aldolase
Corynebacterium ammoniagenes12612HMPREF0281_01493dihydroneopterin aldolase
Corynebacterium callunae15359H924_11290hypothetical protein
Corynebacterium efficiens100395CE2539putative dihydroneopterin aldolase
Corynebacterium glutamicum12168Cgl2693Dihydroneopterin aldolase
Corynebacterium glutamicum12153KIQ_12260hypothetical protein
Corynebacterium matruchotii15360HMPREF0299_7532dihydroneopterin aldolase
Corynebacterium striatum15291HMPREF0308_2214dihydroneopterin aldolase
Corynebacterium terpenotabidum14764A606_01960dihydroneopterin aldolase
Cupriavidus metallidurans102507Rmet_0183dihydroneopterin aldolase
Cystobacter fuscus100088D187_001665putative dihydroneopterin aldolase
Cytophaga hutchinsonii15051CHU_0761dihydroneopterin aldolase
Deinococcus proteolyticus101906Deipr_1895dihydroneopterin aldolase
Edwardsiella tarda105688ET1_09_00190D-erythro-7,8-dihydroneopterin triphosphate epimerase
ET1_14_00290dihydroneopterin aldolase
Enterobacter aerogenes13534EAE_03660bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase
EAE_24500D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
Enterobacter cloacae subsp. cloacae13535ECL_03652D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
ECL_04384bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase
Enterobacter hormaechei105718HMPREF9086_3219dihydroneopterin aldolase
HMPREF9086_3897dihydroneopterin aldolase
Enterococcus haemoperoxidus100709I583_00579dihydroneopterin aldolase
Enterococcus pallens100697I588_03236dihydroneopterin aldolase
Escherichia coli3972EcolC_0641dihydroneopterin aldolase
EcolC_1349dihydroneopterin aldolase
Escherichia coli13500WFL_12200D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
WFL_16245bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase
Escherichia coli12713Y75_2309D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase and dihydroneopterin aldolase
Y75_3024bifunctional dihydroneopterin aldolase and dihydroneopterin triphosphate 2'-epimerase
Escherichia fergusonii102419EFER_0860D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase and dihydroneopterin aldolase
EFER_3003bifunctioal dihydroneopterin aldolase ; dihydroneopterin triphosphate 2'-epimerase
Escherichia hermannii105704EH105704_01_07480D-erythro-7,8-dihydroneopterin triphosphate epimerase
EH105704_19_00110dihydroneopterin aldolase
Fibrobacter succinogenesFisuc_0383dihydroneopterin aldolase
Fimbriimonas ginsengisoliOP10G_3402dihydroneopterin aldolase
Finegoldia magnaFMG_0880bifunctional aldolase-pyrophosphokinase
Fischerella sp.PCC9339_RS0113155dihydroneopterin aldolase
Flavobacterium johnsoniae14942Fjoh_1014dihydroneopterin aldolase
Flexibacter litoralis15988Fleli_3296dihydroneopterin aldolase
Fluviicola taffensis106335Fluta_1540dihydroneopterin aldolase
Frateuria aurantia3245Fraau_2728dihydroneopterin aldolase
Fusobacterium nucleatum subsp. NucleatumFN00722-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Geodermatophilus obscurus13315Gobs_0619dihydroneopterin aldolase
Gloeobacter violaceusglr1487dihydroneopterin aldolase
Gluconacetobacter hansenii14816GXY_13323dihydroneopterin aldolase
Gluconobacter frateurii101659GfraN1_010100000380bifunctional folate synthesis protein
Gordonia aichiensis108223GOACH_01_01740dihydroneopterin aldolase
Gordonia alkanivorans16433GOALK_015_00210dihydroneopterin aldolase
Gordonia amarae15530GOAMR_72_00230dihydroneopterin aldolase
Gordonia amicalis100051GOAMI_36_00170dihydroneopterin aldolase
Gordonia araii100433GOARA_053_00150dihydroneopterin aldolase
Gordonia bronchialis16047Gbro_4014dihydroneopterin aldolase
Gordonia effusa100432GOEFS_076_00340dihydroneopterin aldolase
Gordonia hirsuta16056GOHSU_61_00130dihydroneopterin aldolase
Gordonia namibiensis108229GONAM_34_00270dihydroneopterin aldolase
Gordonia otitidis100426GOOTI_012_00230dihydroneopterin aldolase
Gordonia polyisoprenivorans16320GOPIP_077_01410dihydroneopterin aldolase
Gordonia rhizosphera16068GORHZ_058_00120dihydroneopterin aldolase
Gordonia rubripertincta101908GORBP_059_00510dihydroneopterin aldolase
Gordonia sihwensis108236GSI01S_12_00120dihydroneopterin aldolase
Gordonia soli108243GS4_11_04000dihydroneopterin aldolase
Gordonia sputi100414GOSPT_103_00580dihydroneopterin aldolase
Gordonia terrae100016GOTRE_054_00610dihydroneopterin aldolase
Halobacillus halophilus102448HBHAL_1092dihydroneopterin aldolase
Halomonas elongata15536HELO_2174D-erythro-7,8-dihydroneopterin triphosphate epimerase
HELO_3476dihydroneopterin aldolase
Hylemonella gracilis14920HGR_00340dihydroneopterin aldolase
Hyphomonas neptunium14232HNE_2365dihydroneopterin aldolase
Ignavibacterium album101810IALB_2377Dihydroneopterin aldolase
Intrasporangium calvum12989Intca_06032-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
Jonesia denitrificans15587Jden_21012-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Kineococcus radiotolerans101839Krad_0541dihydroneopterin aldolase
Kineosphaera limosa100340KILIM_093_00060dihydroneopterin aldolase/2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Kitasatospora setae14216KSE_43880putative dihydroneopterin aldolase
Klebsiella pneumoniae14438KPR_2013
KPR_4494
Klebsiella pneumoniae subsp. rhinoscleromatis105682HMPREF0484_2462dihydroneopterin aldolase
HMPREF0484_3494dihydroneopterin aldolase
Kocuria rhizophila103217KRH_19250dihydroneopterin aldolase
Kordia algicida100336KAOT1_16708dihydroneopterin aldolase
Kribbella flavida14399Kfla_6463dihydroneopterin aldolase
Kyrpidia tusciae15312Btus_0104dihydroneopterin aldolase
Kytococcus sedentarius15357Ksed_24750dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Labrenzia aggregata16684SIAM614_28563Dihydroneopterin aldolase
Lactobacillus delbrueckii subsp. bulgaricus13953Ldb0246Dihydroneopterin aldolase
Lactobacillus fermentum15885HMPREF0511_1709dihydroneopterin aldolase
Lactobacillus fermentum3956LAF_1341dihydroneopterin aldolase
Lactobacillus helveticus15019HMPREF0518_0258dihydroneopterin aldolase
Lactobacillus hilgardii15886HMPREF0519_2226dihydroneopterin aldolase
Lactobacillus plantarum subsp. plantarum15891HMPREF0531_12980dihydroneopterin aldolase
Lactobacillus reuteri15892LAR_1213dihydroneopterin aldolase
Leadbetterella byssophila106382Lbys_3185dihydroneopterin aldolase
Lentisphaera araneosaLNTAR_11581dihydroneopterin aldolase
Leuconostoc lactis107866EY7_1058_00040Dihydroneopterin aldolase
Limnochorda pilosa110152LIP_3530dihydroneopterin aldolase
Magnetospirillum gryphiswaldense15271MGR_3198Dihydroneopterin aldolase
Magnetospirillum magnetotacticum15272Magn03004887COG1539: Dihydroneopterin aldolase
Magn03008825COG1539: Dihydroneopterin aldolase
Marinomonas mediterranea103028Marme_1013dihydroneopterin aldolase
Marme_2591dihydroneopterin aldolase
Mariprofundus ferrooxydansSPV1_09949dihydroneopterin aldolase
Marivirga tractuosa15989Ftrac_0094dihydroneopterin aldolase
Meiothermus silvanus106475Mesil_0311dihydroneopterin aldolase
Methylacidiphilum infernorumMinf_1823Dihydroneopterin aldolase
Methylobacterium radiotolerans15690Mrad2831_0512dihydroneopterin aldolase
Micrococcus luteus3333Mlut_01270dihydroneopterin aldolase
Microlunatus phosphovorus101784MLP_48440dihydroneopterin aldolase
Micromonospora aurantiaca16155Micau_5872dihydroneopterin aldolase
Microscilla marina16560M23134_02447dihydroneopterin aldolase
Mobilicoccus pelagius104925MOPEL_074_00710dihydroneopterin aldolase/2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Myroides odoratus14945Myrod_1687dihydroneopterin aldolase
Nakamurella multipartita105858Namu_0851dihydroneopterin aldolase
Niastella koreensis106392Niako_0911dihydroneopterin aldolase
Nitriliruptor alkaliphilusNitalDRAFT_1537dihydroneopterin aldolase
Nitrosomonas europaea14298NE0223Dihydroneopterin aldolase
Nocardiopsis dassonvillei14626Ndas_49742-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Nostoc sp.alr3512dihydroneopterin aldolase
Oceanithermus profundus100410Ocepr_1871dihydroneopterin aldolase
Ochrobactrum anthropi15819Oant_2116dihydroneopterin aldolase
Ochrobactrum intermedium15820OINT_1001190dihydroneopterin aldolase
Paenibacillus alvei3343PAV_2c06590dihydroneopterin aldolase FolB
Paenibacillus peoriae15541PpeoK3_010100024099dihydroneopterin aldolase
Paenibacillus polymyxa15309PPT_00380dienelactone hydrolase
Pedobacter heparinus12017Phep_2328dihydroneopterin aldolase
Pedobacter saltans100064Pedsa_1477dihydroneopterin aldolase
Phaeobacter gallaeciensis16654PGA1_c06530dihydroneopterin aldolase-like protein
Prochlorococcus marinus subsp. marinusPro_1070Dihydroneopterin aldolase
Propionibacterium acidipropionici12425PACID_28460Dihydroneopterin aldolase
Propionibacterium avidum15671HMPREF9153_1337dihydroneopterin aldolase
Proteus mirabilis105697HMPREF0693_2573dihydroneopterin aldolase
Providencia alcalifaciens105687PROVALCAL_02246dihydroneopterin aldolase
Pseudomonas putida100650PP_0392dihydroneopterin aldolase
Pseudomonas stutzeri14165PSTAB_0612dihydroneopterin aldolase
PSTAB_1039D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
PSTAB_1870D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
Rahnella aquatilis105701Rahaq2_0638dihydroneopterin aldolase
Renibacterium salmoninarum15589RSal33209_3212dihydroneopterin aldolase
Rhizobium etli15573RHE_CH02335dihydroneopterin aldolase protein
Rhizobium sp.101917NGR_c16590dihydroneopterin aldolase
Rhizobium tropici15247RTCIAT899_CH10000dihydroneopterin aldolase
Rhodobacter capsulatus16581RCAP_rcc01210dihydroneopterin aldolase
RCAP_rcc02419dihydroneopterin aldolase
Rhodobacter sphaeroides12203RSP_1861probable dihydroneopterin aldolase
Rhodococcus erythropolis100887RER_06280dihydroneopterin aldolase
Rhodococcus opacus108011ROP_43260dihydroneopterin aldolase
Roseobacter denitrificans15277RD1_1950dihydroneopterin aldolase, putative
Roseobacter litoralis15278RLO149_c010450dihydroneopterin aldolase-like protein
Rothia dentocariosa12531HMPREF0733_10713dihydroneopterin aldolase
Rothia mucilaginosa15673ROTMU0001_1804dihydroneopterin aldolase
Rubrobacter xylanophilus100952Rxyl_2579dihydroneopterin aldolase
Saccharomonospora azurea14651SacazDRAFT_02325dihydroneopterin aldolase
Saccharomonospora cyanea14841SaccyDRAFT_4694dihydroneopterin aldolase
Saccharomonospora glauca14831SacglDRAFT_03952dihydroneopterin aldolase
Saccharomonospora viridis12207Svir_35620dihydroneopterin aldolase
Saccharopolyspora erythraea13426SACE_0399dihydroneopterin aldolase
Saccharopolyspora spinosa15153SspiN1_010100021128dihydroneopterin aldolase
Saccharothrix espanaensis15066BN6_03530hypothetical protein
Salinibacter ruberSRU_0761dihydroneopterin aldolase
Salinispora arenicola105043Q5S_3013_00010dihydroneopterin aldolase
Salinispora tropica105044Strop_4296dihydroneopterin aldolase
Sanguibacter keddieii16158Sked_32060dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Selenomonas ruminantium subsp. lactilytica103574SELR_22020putative dihydroneopterin aldolase
SELR_27260putative dihydroneopterin aldolase
Serratia odorifera102598HMPREF0758_1935dihydroneopterin aldolase
HMPREF0758_2769dihydroneopterin aldolase
Shimwellia blattae105725EB105725_04_00400D-erythro-7,8-dihydroneopterin triphosphate epimerase
EB105725_20_00070dihydroneopterin aldolase
Solitalea canadensis15130Solca_1751dihydroneopterin aldolase
Sphingobacterium spiritivorum14948HMPREF0766_12953dihydroneopterin aldolase
Sphingobium japonicum101211SJA_C1-14840putative dihydroneopterin aldolase
SJA_C2-01180dihydroneopterin aldolase
Sphingobium sp.103272SLG_00860hypothetical protein
Sphingomonas echinoides15742SechA1_010100003710dihydroneopterin aldolase
SechA1_010100017113dihydroneopterin aldolase
Sphingomonas wittichii105917Swit_0115dihydroneopterin aldolase
Swit_4785dihydroneopterin aldolase
Sporichthya polymorpha12702Spopo_30_19750Dihydroneopterin aldolase
Stackebrandtia nassauensis102104Snas_6217dihydroneopterin aldolase
Staphylococcus epidermidis12993SE_22687,8-dihydroneopterin aldolase
Staphylococcus saprophyticus subsp. saprophyticus102446SSP2241dihydroneopterin aldolase
Starkeya novella14993Snov_0744dihydroneopterin aldolase
Streptococcus equinus12553HMPREF0819_0600dihydroneopterin aldolase
Streptococcus mitis106071SM12261_0580bifunctional folate synthesis protein
Streptomyces avermitilis14893SAV4670putative dihydroneopterin aldolase
Streptomyces cattleya14057SCAT_2647dihydroneopterin aldolase
Streptomyces clavuligerus13307SCLAV_2409Putative dihydroneopterin aldolase
Streptomyces ghanaensis15414SSFG_03188dihydroneopterin aldolase
Streptomyces mobaraensis13819H340_05544dihydroneopterin aldolase
Streptomyces pristinaespiralis13074SSDG_06475dihydroneopterin aldolase
Streptomyces purpureus13925STRPU_11_01770Putative dihydroneopterin aldolase
Streptomyces sviceus13980SSEG_11018dihydroneopterin aldolase
Streptomyces venezuelae13096SVEN_3252Dihydroneopterin aldolase
Streptosporangium roseum3776Sros_9171Dihydroneopterin aldolase
Synechococcus elongatusSynpcc7942_0040dihydroneopterin aldolase Dihydroneopterin aldolase
Synechocystis sp.slr1626hypothetical protein
Thauera linaloolentis102519C666_04830dihydroneopterin aldolase
Thermanaerovibrio acidaminovoransTaci_0793dihydroneopterin aldolase
Thermobispora bispora14880Tbis_3443dihydroneopterin aldolase
Thermomicrobium roseumtrd_1326dihydroneopterin aldolase
Thermomonospora curvata15933Tcur_4501dihydroneopterin aldolase
Thermus thermophilus101084TTHA0190dihydroneopterin aldolase
Thermus thermophilus101085TT_C1796dihydroneopterin aldolase
Tsukamurella paurometabola16120Tpau_0562dihydroneopterin aldolase
Turicella otitidis106139HMPREF9719_01343dihydroneopterin aldolase
Vibrio alginolyticus15630N646_2567putative dihydroneopterin aldolase FolB
Vibrio ichthyoenteri15847VII00023_12616dihydroneopterin aldolase
Vibrio metschnikovii103153VIB_002025dihydroneopterin aldolase
Vibrio orientalis15638VIOR3934_09850dihydroneopterin aldolase
Vibrio tubiashii15644VITU9109_25800dihydroneopterin aldolase
Vibrio vulnificus15645B736_10720dihydroneopterin triphosphate 2'-epimerase
Weeksella virosa16016Weevi_1088dihydroneopterin aldolase
Xenococcus sp.Xen7305DRAFT_00039100dihydroneopterin aldolase
Xylanimonas cellulosilytica107835Xcel_29842-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase
Yersinia bercovieri105717yberc0001_34710Dihydroneopterin aldolase
Yersinia rohdei105715yrohd0001_16960Dihydroneopterin aldolase
Zimmermannella faecalis15706G328_13145hypothetical protein
Zymomonas mobilis subsp. pomaceae13757Zymop_0228dihydroneopterin aldolase